الصفحة الرئيسية>>Signaling Pathways>> Immunology/Inflammation>> NF-κB>>CORM-3

CORM-3

رقم الكتالوجGC38031

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CORM-3 التركيب الكيميائي

Cas No.: 475473-26-8

الحجم السعر المخزون الكميّة
1mg
92٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

CORM-3, a water-soluble carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels[1][2][3].

[1]. Foresti R, et al. Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule. Br J Pharmacol. 2004 Jun;142(3):453-60. [2]. Lee DW, et al. Carbon monoxide regulates glycolysis-dependent NLRP3 inflammasome activation in macrophages. Biochem Biophys Res Commun. 2017 Nov 18;493(2):957-963. [3]. Huang Y, et al. Carbon monoxide (CO) inhibits hydrogen peroxide (H2O2)-induced oxidative stress and the activation of NF-κB signaling in lens epithelial cells. Exp Eye Res. 2018 Jan;166:29-39.

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