CleanAmp dNTP Mix

CleanAmp dNTPs significantly reduce or even eliminate mis-priming and primer dimer formation during PCR by blocking nucleotide incorporation by DNA polymerase until elevated temperatures are achieved. Like other Hot Start approaches, these modified nucleoside triphosphates are activated by the elevated temperatures of PCR thermal cycling. CleanAmp dNTPs offer precise control at the start of PCR thermal cycling thereby vastly improving PCR specificity. CleanAmp dNTP Mix contains dATP, dCTP, dGTP and dTTP at 10 mM each. Each dNTP is analyzed separately by AX-HPLC, RP-HPLC, 31P NMR and Mass Spec, and the dNTP mix is further tested in a standardized PCR assay.