IFNAlpha Human 2a Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19241 Dalton.The difference between IFNA2A and IFNA2B is in the amino acid present at position 23. IFN-alpha 2a has a lysine at that position 23 while IFN-alpha 2b has arginine.The IFNA2Agene was obtained from human leukocytes.The IFNA2A is purified by proprietary chromatographic techniques.
المراجع (Citations)
لا تتوفر حاليًا مراجع لهذا المنتج. فيما يلي مجموعة مختارة من المنشورات التي تستشهد بمنتجات GlpBio.الوصف (Description)
وثائق المنتج (Product Documents)
الخصائص الكيميائية (Chemical Properties)
المصدر
E. coli
المظهر الفيزيائي
Sterile Filtered White lyophilized (freeze-dried) powder.
شروط الشحن
Shipped at ice.
المرادفات
Leukocyte IFN; B cell IFN; Type I IFN; IFNA2; IFN-a 2a.
تسلسل الأحماض الأمينية
CDLPQTHSLGSRRTLMLLAQMRKISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEM IQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAV RKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE.N-terminal methionine has been completely removed enzymatically.
الوزن الجزيئي الظاهري
~19.2 kDa, on SDS-PAGE under reducing conditions. Da
الثبات
Upon receiving, this product remains stable for 6 months at lower than -70°C. Upon reconstitution, the product should be stable for 1 week at 4°C or for 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
النشاط البيولوجي
ED50 < 0.1 ng/ml, measured by a cytotoxicity assay using TF-1 Cells, corresponding to a specific activity of > 1.0 × 107U/mg.
التركيبة
Lyophilized after extensive dialysis against PBS.
Reviews
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