Imidapril HCl (Synonyms: TA-6366) |
| رقم الكتالوجGC13078 |
Imidapril HCl (TA-6366) هو إنزيم نشط عن طريق الفم لتحويل الأنجيوتنسين (ACE) ومثبط MMP-9.
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Cas No.: 89396-94-1
Sample solution is provided at 25 µL, 10mM.
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Imidapril hydrochloride (TA-6366) is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
As a prodrug, Imidapril is converted by hydrolysis in the liver into its active form imidaprilat. Imidaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Imidaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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