Enzyme Substrates

3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors, in order to study structure-activity relationships.

(D)2-Rh 110 is a fluorogenic caspase substrate.

(Z-IETD)2-Rh 110 is a fluorogenic substrate for caspase-8.

Carbohydrates conjugated with 2-chloro-4-nitrophenyl (CNP) serve as chromogenic substrates in assays for enzymes that release CNP from the conjugated carbohydrate.

2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis.

3-Hydroxyglutaric acid dimethyl ester is a prochiral substrate and an esterified derivative of 3-hydroxyglutaric acid.

4-Methylumbelliferyl-α-L-iduronide 2-sulfate (4-MU-α-IdoA 2-sulfate) is a fluorogenic substrate of α-L-iduronidase that has been used in an assay to detect Hurler syndrome.

4-Nitrophenyl β-D-Cellobioside is a synthetic chromogenic substrate used for the determination of β-glucosidase activity. 4-Nitrophenyl β-D-Cellobioside is widely used in biochemical research to study the enzymatic hydrolysis of glycosidic bonds.

4-Nitrophenyl β-D-cellotrioside is a chromogenic substrate for endoglucanases and cellobiohydrolases.

N-acetyl-D-galactosaminidase catalyzes the cleavage of N-acetylglucosamine (GlcNAc), the monomeric unit of the polymer chitin.

Ac-DMQD-AMC is a fluorogenic substrate for caspase-3.

Ac-IEPD-AMC is a fluorogenic substrate for granzyme B.

Ac-LEHD-AFC is a fluorogenic substrate that can be cleaved by caspase-4, -5, and -9.

Ac-RLR-AMC is a fluorogenic substrate for the 26S proteasome.

Ac-VDVAD-pNA is a colorimetric substrate for caspase-2.

Ac-WEAD-pNA is a colorimetric substrate for caspase-1 and caspase-4.

Autocamtide 2 is a peptide substrate for calcium/calmodulin-dependent protein kinase (CaMK) and CaMKII.

Dabcyl-GABA-RPKPVE-Nva-WR-Glu(EDANS)-AK-NH2 is a fluorogenic substrate for matrix metalloproteinase-3 (MMP-3).

Dabcyl-RGVVNASSRLA-EDANS is a fluorogenic substrate for human cytomegalovirus (HCMV) protease.

Decanoyl m-Nitroaniline (DemNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.

Dieosinediglutathione is the product of glutathione disulfide and eosin isothiocyanate which has been purified and lyophilized.

Dnp-GPLGMRGL-NH2 is a peptide substrate for matrix metalloproteinase-13 (MMP-13) with a kcat/Km value of 4,200,000 M-1s-1.

Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9.

Dnp-PLG-Cys(Me)-HA-DArg-NH2 is a peptide substrate for matrix metalloproteinase-1 (MMP-1).