Lusianthridin |
| رقم الكتالوجGC61014 |
Lusianthridin ، مركب نقي من Dendrobium venustum ، له تأثير مضاد للهجرةيعزز Lusianthridin تدهور c-Myc من خلال تثبيط إشارات Src-STAT3
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Cas No.: 87530-30-1
Sample solution is provided at 25 µL, 10mM.
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Lusianthridin, a pure compound from Dendrobium venustum, have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling[1].
Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells[1].Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively[1]. Cell Viability Assay[1] Cell Line: The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells[1].0-100 μM.
[1]. Narumol Bhummaphan, et al. Targeting of Lung Cancer Stem Cells via Src-STAT3 Suppression. Phytomedicine. 2019 Sep;62:152932.
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