NOTA-P2-RM26 is an antagonist of Bombesin analogs, and the gastrin-releasing peptide receptor ( GRPR/BB2 ) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111 In and 68 Ga for prostate cancer imaging studies using PET and SPECT/CT [1].
References:
[1]. Varasteh Z, et al. Synthesis and characterization of a high-affinity NOTA-conjugated bombesin antagonist for GRPR-targeted tumor imaging. Bioconjug Chem. 2013 Jul 17;24(7):1144-53.
References:
[1]. Varasteh Z, et al. Synthesis and characterization of a high-affinity NOTA-conjugated bombesin antagonist for GRPR-targeted tumor imaging. Bioconjug Chem. 2013 Jul 17;24(7):1144-53.
















