Olpadronic acid (Olpadronate) is an orally active amino-bisphosphonate and inhibits bone resorption. Olpadronic acid also prevents bone destruction and tumor growth in the skeletal prostate cancer mouse model. Olpadronic acid can be used for research of osteoporosis, malignancies and rheumatoid arthritis[1][2].
References:
[1]. Roldán EJ, et al. Olpadronate: a new amino-bisphosphonate for the treatment of medical osteopathies. Expert Opin Investig Drugs. 1998 Sep;7(9):1521-38.
[2]. Yang M, et al. The bisphosphonate olpadronate inhibits skeletal prostate cancer progression in a green fluorescent protein nude mouse model. Clin Cancer Res. 2006 Apr 15;12(8):2602-6.