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Poly(A) polymerase

رقم الكتالوجGC81655 Copy One-Click Copy Product Info

Poly(A) polymerase catalyzes the incorporation of ATP into the RNA 3' end in the form of AMP, that is, adding a polyadenosine tail at the RNA 3' end.

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Poly(A) polymerase التركيب الكيميائي

Cas No.: 9026-30-6

الحجم السعر المخزون الكميّة
100U
153٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.



Description of Poly(A) polymerase

Poly(A) polymerase catalyzes the incorporation of ATP into the RNA 3' end in the form of AMP, that is, adding a polyadenosine tail at the RNA 3' end. Poly(A) polymerase increases RNA stability and increases mRNA translation efficiency in eukaryotic cells. Poly(A) polymerase has high tailing efficiency and can add 20-200 A bases to the 3' end of RNA [1] [2].

In Vitro, Table. Package Contents Specification Type Components Volume Quantity 100 U A Poly(A) Polymerase (5U/μL) 100 U 1 100 U B 10 x Poly(A) Polymerase Buffer 1 mL 1 100 U C ATP (10 mM) 0.1 mL 1

References:
[1]. Li W, et al. The novel poly(A) polymerase Star-PAP is a signal-regulated switch at the 3'-end of mRNAs. Adv Biol Regul. 2013 Jan;53(1):64-76.
[2]. Chen LS, et al. Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues. Biochem Pharmacol. 2010 Mar 1;79(5):669-77.

Chemical Properties of Poly(A) polymerase

Cas No. 9026-30-6 SDF
Formula M.Wt
الذوبان Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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