Polysarcosine50 is an amine-functionalized hydrophilic polymer.1 It has been used in the synthesis of catechol-functionalized copolypeptoids that can be used to solubilize manganese oxide nanoparticles in aqueous solvents. Surface modification of liposomes with polysarcosine polymers between 10 and 400 units long have been used to increase circulation half-life.2
References:
[1]. Gebru, H., Wang, X., Li, Z., et al.Br?nsted base mediated one-pot synthesis of catechol-ended amphiphilic polysarcosine-b-poly(N-butyl glycine) diblock copolypeptoids.Pure Appl. Chem.91(3)363-374(2019).
[2]. Weber, B., Birke, A., Fischer, K., et al.Solution properties of polysarcosine: From absolute and relative molar mass determinations to complement activationMacromolecules51(7)2653–2661(2018).