الصفحة الرئيسية>>Signaling Pathways>> PI3K/Akt/mTOR Signaling>> PDK-1>>PS47

PS47

رقم الكتالوجGC63155

PS47 هو أيزومر E غير نشط لـ PS48

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PS47 التركيب الكيميائي

Cas No.: 1180676-33-8

الحجم السعر المخزون الكميّة
5 mg
72٫00
متوفر
10 mg
115٫00
متوفر
25 mg
230٫00
متوفر
50 mg
368٫00
متوفر
100 mg
590٫00
متوفر

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مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48[1][2].

PS47 shows very low binding affinity or no binding to PDK1 (Kd>200 µM)[1].

[1]. Hindie V, et, al. Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. Nat Chem Biol. 2009 Oct;5(10):758-64.
[2]. Pastor-Flores D, et, al. PIF-pocket as a target for C. albicans Pkh selective inhibitors. ACS Chem Biol. 2013 Oct 18;8(10):2283-92.

مراجعات

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Average Rating: 5 ★★★★★ (Based on Reviews and 37 reference(s) in Google Scholar.)

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