(R)-(-)-Chlorpheniramine maleate is an enantiomer of Chlorpheniramine maleate. Chlorpheniramine maleate is a H1 antihistamines. (R)-(-)-Chlorpheniramine maleate can be used for allergic diseases such as rhinitis and urticaria research [1] [2].
References:
[1]. Sakurai E, et al. The optical resolution of racemic chlorpheniramine and its stereoselective pharmacokinetics in rat plasma. J Pharm Pharmacol. 1992 Jan;44(1):44-7.
[2]. Kim J, et al. Inhibitory effects of antihistamines, diphenhydramine and chlorpheniramine, on proton currents in BV2 microglial cells. Eur J Pharmacol. 2017 Mar 5;798:122-128.
References:
[1]. Sakurai E, et al. The optical resolution of racemic chlorpheniramine and its stereoselective pharmacokinetics in rat plasma. J Pharm Pharmacol. 1992 Jan;44(1):44-7.
[2]. Kim J, et al. Inhibitory effects of antihistamines, diphenhydramine and chlorpheniramine, on proton currents in BV2 microglial cells. Eur J Pharmacol. 2017 Mar 5;798:122-128.