GLPBio

Apoptosis

Research Areas

Products Related to Apoptosis(675)

  • GC79230 structure
    GC79230BBO-11818
    CAS: 3029443-36-2
    Purity: >99.50%

    BBO-11818 is an orally active, highly selective (relative to NRAS and HRAS ), non-covalent pan- KRAS inhibitor ( IC 50 =28-120 nM).

  • GC79231 structure
    GC79231RMC-4998 TFA
    Purity: >99.00%

    RMC-4998 TFA is an orally active inhibitor targeting the active or GTP-bound state of the KRAS G12C mutant.

  • GC79326 structure
    GC79326Tirzepatide sodium
    Purity: >98.00%

    Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide ( GIP ) and glucagon-like peptide-1 ( GLP-1 ) receptor agonist.

  • GC79337 structure
    GC79337ZSTK3744
    Purity: >98.00%

    ZSTK3744 is an aryl hydrocarbon receptor ( AhR ) agonist.

  • GC79338 structure
    GC79338PL120131 acetate
    Purity: >99.50%

    PL120131 acetate is a PD-1 antagonist, can specifically blocking the interaction between PD-1 and PD-L1, thereby effectively inhibiting the PD-1-mediated apoptosis signaling pathway.

  • GC79339 structure
    GC79339Anti-CD160 Antibody (MAT 302)
    Purity: >97.00%

    Anti-CD160 Antibody (MAT 302) (CL1-R2) is a human monoclonal antibody targeting CD160.

  • GC79451 structure
    GC79451JP-11646
    CAS: 1902983-63-4
    Purity: >98.50%

    JP-11646 is a pan-PIM inhibitor with increased potency against PIM2 ( IC 50 = 0.5 nM).

  • GC79463 structure
    GC79463NGI-189
    CAS: 2763063-26-7
    Purity: >99.00%

    NGI‑189 is a selective OST‑A inhibitor.

  • GC79465 structure
    GC79465STAT3-IN-52 hydrochloride
    Purity: >96.00%

    STAT3-IN-52 hydrochloride is an orally active STAT3 inhibitor with a K i value of 2.42 μM.

  • GC79473 structure
    GC79473AT-051/43421517
    CAS: 1241957-37-8
    Purity: >99.50%

    AT-051/43421517 is a cytoprotective agent and apoptosis inhibitor that binds to human phosphoglycerate kinase 1 ( hPgk1 ).

  • GC79474 structure
    GC79474(E/Z)-ASK1-IN-4
    CAS: 324566-92-9
    Purity: >98.00%

    (E/Z)-ASK1-IN-4 is an isomer of ASK1-IN-4.

  • GC79475 structure
    GC79475MKK7-JNK activator 1
    CAS: 3100092-62-1
    Purity: >99.50%

    MKK7-JNK activator 1 (Compound 10) is a MKK7-JNK pathway activator.

  • GC79486 structure
    GC79486Bacoside A (mixture)
    Purity: >98.00%

    Bacoside A (mixture) is a mixture composed of Bacoside A3, Bacopaside II, Bacopaside X and Bacopasaponin C.

  • GC79487 structure
    GC79487(S)-Verapamil
    CAS: 36622-29-4
    Purity: >99.50%

    (S)-Verapamil ((S)-(-)-Verapamil) is an orally active MRP1 (ABCC1) modulator with a K d value of 113 nM for hamster MRP1.

  • GC79504 structure
    GC79504(R)-Verapamil
    CAS: 38321-02-7
    Purity: >98.50%

    (R)-Verapamil (Dexverapamil) is an optically enantiomer of the oral-active Verapamil.

  • GC79519 structure
    GC79519SKF-96365
    CAS: 162849-90-3
    Purity: >99.50%

    SKF-96365 is a TRPC channel antagonist and store-operated calcium entry ( SOCE ) inhibitor.

  • GC79549 structure
    GC79549FJ9
    CAS: 873841-43-1
    Purity: >98.50%

    FJ9 is a NHERF1/PDZ inhibitor with human NHERF1 PDZ1 IC 50 1540 μM, NHERF1 PDZ2 IC 50 160 μM, and Frizzled-7-Dishevelled PDZ complex K i 10 μM.

  • GC79577 structure
    GC79577PFKFB4-IN-1
    CAS: 2664831-55-2
    Purity: >99.50%

    PFKFB4-IN-1 is a potent and selective ATP-competitive PFKFB4 inhibitor ( IC 50 = 4.50 μM) that reduces intracellular PFKFB4 protein levels.

  • GC79578 structure
    GC79578PrCP-7414
    CAS: 1252037-41-4
    Purity: >99.50%

    PrCP-7414 is a prolyl carboxypeptidase ( PRCP ) inhibitor.

  • GC79709 structure
    GC79709HK2-IN-4
    CAS: 2748366-80-3
    Purity: >99.50%

    HK2-IN-4 is a selective hexokinase 2 ( HK2 ) inhibitor with an IC 50 value of 0.79 μM and a K d value of 0.41 μM.

  • GC79757 structure
    GC79757ALOX5 stabilizer-1 TFA
    Purity: >98.00%

    ALOX5 stabilizer-1 TFA is an arachidonate 5-lipoxygenase ( ALOX5 ) stabilizer with a K d of 7.26 μM.

  • GC79758 structure
    GC79758PAI-1-IN-1
    CAS: 1247823-40-0
    Purity: >99.00%

    PAI-1-IN-1 is an orally active and specific PAI-1 inhibitor with an IC 50 of <6.95 μM.

  • GC79806 structure
    GC79806TKL002
    CAS: 3098518-95-4
    Purity: >98.00%

    TKL002 is a blood-brain barrier-permeable inhibitor of the CTH/H 2 S/NF-κB/EMT signaling axis.

  • GC79807 structure
    GC79807RP-182 acetate
    Purity: >98.50%

    RP-182 acetate is a synthetic immunomodulatory peptide that exerts anti-tumor effects by targeting the mannose receptor CD206 ( K d = 8 μM) on the surface of tumor-associated macrophages (TAMs).