Reactive Oxygen Species
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Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.
ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Products Related to Reactive Oxygen Species(505)
- GC49372Kaempferol 7-neohesperidosideCAS: 17353-03-6Purity: >95.00%
A flavonoid glycoside with antioxidant and anticancer activities
- GC49420Gallic Acid-d2CAS: 294660-92-7Purity: >99.00%
An internal standard for the quantification of gallic acid
- GC49422PAR2 (1-6) amide (human) (trifluoroacetate salt)CAS: 2379569-17-0Purity: >95.00%
A peptide agonist of PAR2
- GC49426Taurine-d4CAS: 342611-14-7Purity: >99.00%
An internal standard for the quantification of taurine
- GC49436L-3-n-ButylphthalideCAS: 3413-15-8Purity: >99.00%
A phthalide with antiplatelet and neuroprotective activities
- GC49486Meglutol-d3CAS: 59060-36-5Purity: >99.00%
An internal standard for the quantification of meglutol
- GC49855Harmalol (hydrochloride hydrate)CAS: 6028-00-8Purity: >98.00%
A β-carboline alkaloid and an active metabolite of harmaline
- GC52027IsolariciresinolCAS: 548-29-8Purity: >98.00%
يمكن استخدام Isolariciresinol ((+) -Cyclolariciresinol) في أبحاث التهاب الروماتيزم.
- GC52073N-formyl-2-AminophenolCAS: 2843-27-8Purity: >98.00%
A bacterial secondary metabolite with antioxidant activity
- GC52081ChamazuleneCAS: 529-05-5Purity: >98.00%
شامازولين مركب طبيعي ، وهو مثبط من نوع مضادات الأكسدة لتكوين الليكوترين ب 4
- GC52190Imidazole Ketone ErastinCAS: 1801530-11-9Purity: >98.00%
Imidazole Ketone Erastin is an effective and metabolically stable system xc- inhibitor and ferroptosis inducer.
- GC522275-(3',4'-Dihydroxyphenyl)-γ-ValerolactoneCAS: 21618-92-8Purity: >95.00%
An active metabolite of various polyphenols
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49372 | Kaempferol 7-neohesperidoside | 17353-03-6 | >95.00% | |
A flavonoid glycoside with antioxidant and anticancer activities | ||||
| GC49420 | Gallic Acid-d2 | 294660-92-7 | >99.00% | |
An internal standard for the quantification of gallic acid | ||||
| GC49422 | PAR2 (1-6) amide (human) (trifluoroacetate salt) | 2379569-17-0 | >95.00% | |
A peptide agonist of PAR2 | ||||
| GC49426 | Taurine-d4 | 342611-14-7 | >99.00% | |
An internal standard for the quantification of taurine | ||||
| GC49436 | L-3-n-Butylphthalide | 3413-15-8 | >99.00% | |
A phthalide with antiplatelet and neuroprotective activities | ||||
| GC49486 | Meglutol-d3 | 59060-36-5 | >99.00% | |
An internal standard for the quantification of meglutol | ||||
| GC49500 | Stobadine | 85202-17-1 | >98.00% | |
A pyridoindole antioxidant | ||||
| GC49521 | MHY553 | 6265-56-1 | >98.00% | |
An agonist of PPARα | ||||
| GC49557 | Cu-GTSM | 68341-14-0 | >95.00% | |
A copper-containing compound with diverse biological activities | ||||
| GC49560 | L6H21 | 24533-47-9 | >98.00% | |
L6H21 ، مشتق Chalcone ، هو مثبط تمايز النخاعي 2 (MD-2) النشط عن طريق الفم ، والقوي والمحدد | ||||
| GC49597 | Leukotriene B4-d5 | - | >99.00% | |
An internal standard for the quantification of LTB 4 | ||||
| GC49708 | Biliverdin (technical grade) | 114-25-0 | >70.00% | |
A bile pigment | ||||
| GC49790 | Reuterin | 2134-29-4 | >98.00% | |
Reuterin هو عامل مضاد للميكروبات واسع الطيف نشط ضد البكتيريا موجبة الجرام وسالبة الجرام ، وكذلك الخمائر والعفن والأوليات | ||||
| GC49849 | 3-Aminosalicylic Acid | 570-23-0 | >98.00% | |
A salicylic acid derivative | ||||
| GC49855 | Harmalol (hydrochloride hydrate) | 6028-00-8 | >98.00% | |
A β-carboline alkaloid and an active metabolite of harmaline | ||||
| GC49864 | 6-Methylpterin | 708-75-8 | >98.00% | |
A derivative of folic acid | ||||
| GC49868 | D-α-Tocopheryl Quinone | 7559-04-8 | >98.00% | |
An oxidative metabolite of vitamin E | ||||
| GC52007 | N-hydroxylamine Dapsone | 32695-27-5 | >98.00% | |
An active metabolite of dapsone | ||||
| GC52027 | Isolariciresinol | 548-29-8 | >98.00% | |
يمكن استخدام Isolariciresinol ((+) -Cyclolariciresinol) في أبحاث التهاب الروماتيزم. | ||||
| GC52073 | N-formyl-2-Aminophenol | 2843-27-8 | >98.00% | |
A bacterial secondary metabolite with antioxidant activity | ||||
| GC52081 | Chamazulene | 529-05-5 | >98.00% | |
شامازولين مركب طبيعي ، وهو مثبط من نوع مضادات الأكسدة لتكوين الليكوترين ب 4 | ||||
| GC52164 | Cu-ATSP | 68341-12-8 | >98.00% | |
Cu-ATSP ، مثبط قوي لموت الخلايا الحديديّة ، أقوى بحوالي 20 ضعفًا من CuATSM. | ||||
| GC52190 | Imidazole Ketone Erastin | 1801530-11-9 | >98.00% | |
Imidazole Ketone Erastin is an effective and metabolically stable system xc- inhibitor and ferroptosis inducer. | ||||
| GC52227 | 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone | 21618-92-8 | >95.00% | |
An active metabolite of various polyphenols | ||||