Styrene-divinylbenzene sulfonated copolymer is a cation exchange resin prepared from sulfonic acid group-containing microporous styrene/divinylbenzene (DVB) copolymer. Styrene-divinylbenzene sulfonated copolymer serves as the core matrix material for most bilirubin adsorbents. It also acts as a hydrophilic cell immobilization carrier, whose porous structure provides an ideal environment for microbial growth and biochemical reactions [1] [2].
In Vitro, Styrene-divinylbenzene sulfonated copolymer serves as a matrix for multiple modified bilirubin adsorbents, with total bilirubin clearance ranging from 37% to 92% depending on additional modifications and coatings[2].
References:
[1]. Koseoglu-Imer DY, et al. Immobilization of Acidithiobacillus ferrooxidans on sulfonated microporous poly(styrene-divinylbenzene) copolymer with granulated activated carbon and its use in bio-oxidation of ferrous iron. Mater Sci Eng C Mater Biol Appl. 2013;33(1):53-58.
[2]. Wang Y, et al. Bilirubin Removal by Polymeric Adsorbents for Hyperbilirubinemia Therapy. Macromol Biosci. 2023;23(5):e2200567.
In Vitro, Styrene-divinylbenzene sulfonated copolymer serves as a matrix for multiple modified bilirubin adsorbents, with total bilirubin clearance ranging from 37% to 92% depending on additional modifications and coatings[2].
References:
[1]. Koseoglu-Imer DY, et al. Immobilization of Acidithiobacillus ferrooxidans on sulfonated microporous poly(styrene-divinylbenzene) copolymer with granulated activated carbon and its use in bio-oxidation of ferrous iron. Mater Sci Eng C Mater Biol Appl. 2013;33(1):53-58.
[2]. Wang Y, et al. Bilirubin Removal by Polymeric Adsorbents for Hyperbilirubinemia Therapy. Macromol Biosci. 2023;23(5):e2200567.