Thyroid hormone. Promotes differentiation of oligodendroglial precursor cells in neonatal rats and promotes maturation of hiPSC-derived cardiomyocytes. Used in protocols to generate cortical spheroids from hPSCs. Sodium salt also available.
Marta et al (1998) Sustained neonatal hyperthyroidism in the rat affects myelination in the central nervous system. J.Neurosci.Res. 53 251 PMID:9671982 |Madhavan et al (2018) Induction of myelinating oligodendrocytes in human cortical spheroids. Nat Methods. 15 700 PMID:30046099 |Yang et al (2014) Tri-iodo-L-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells. J.Mol.CellCardiol. 72 296 PMID:24735830