trans-Sobrerol (NRM-331) is a potent mucofluidifying agent. trans-Sobrerol demonstrates an anti-amnesic effect by enhancing hippocampal cholinergic signaling, alongside exhibiting anti- tau and anti- Aβ synthesis properties. trans-Sobrerol mitigates memory impairment induced by Scopolamine. trans-Sobrerol can be used in the research of Alzheimer's disease [1] [2].
References:
[1]. Ansari A, et al. Sobrerol Improves Memory Impairment in the Scopolamine-Induced Amnesia Mouse Model. Int J Mol Sci. 2025 May 12;26(10):4613.
[2]. Ventura P, et al. The metabolism of trans-sobrerol in the rat. Xenobiotica. 1983 Mar;13(3):139-46.
References:
[1]. Ansari A, et al. Sobrerol Improves Memory Impairment in the Scopolamine-Induced Amnesia Mouse Model. Int J Mol Sci. 2025 May 12;26(10):4613.
[2]. Ventura P, et al. The metabolism of trans-sobrerol in the rat. Xenobiotica. 1983 Mar;13(3):139-46.