Ascr#9 is a small-molecule pheromone belonging to the ascaroside family, and it is widely present in nematodes. Ascr#9 promotes dispersal or elicits avoidance behavior in various nematode species (such as Caenorhabditis elegans and entomopathogenic nematodes), suggesting that individuals evacuate from adverse environments. Ascr#9 exhibits repellent potential in Meloidogyne incognita [1] [2].
In Vitro, Ascr#9 (0.5 μM; 1 hour) significantly increases the dispersal rate of Meloidogyne incognita second-stage juveniles[1]. Ascr#9 (0.5 μM; 1 hour) induces differential expression of Meloidogyne incognita second-stage juveniles, affecting pathways like neuroactive ligand-receptor interaction and olfactory transduction[1].
References:
[1]. Rao Z, et al. Meloidogyne incognita genes involved in the repellent behavior in response to ascr#9. Sci Rep. 2024;14(1):25706. Published 2024 Oct 28.
[2]. Bose N, et al. Natural variation in dauer pheromone production and sensing supports intraspecific competition in nematodes. Curr Biol. 2014;24(13):1536-1541.
In Vitro, Ascr#9 (0.5 μM; 1 hour) significantly increases the dispersal rate of Meloidogyne incognita second-stage juveniles[1]. Ascr#9 (0.5 μM; 1 hour) induces differential expression of Meloidogyne incognita second-stage juveniles, affecting pathways like neuroactive ligand-receptor interaction and olfactory transduction[1].
References:
[1]. Rao Z, et al. Meloidogyne incognita genes involved in the repellent behavior in response to ascr#9. Sci Rep. 2024;14(1):25706. Published 2024 Oct 28.
[2]. Bose N, et al. Natural variation in dauer pheromone production and sensing supports intraspecific competition in nematodes. Curr Biol. 2014;24(13):1536-1541.