BMS-223131 is a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels. BMS-223131 effectively reduced stress-induced colonic motility and visceral nociception supporting the potential utility of maxi-K channel openers for the treatment of bowel disorders involving dysfunctional motility and visceral sensitivity.
BMS-223131
Catalog No.: GB62296Purity:>98%Synonyms: BMS-223131; BMS 223131; BMS223131
BMS-223131 is a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 275375-69-4
1mgIn Stock
$150.00
1
5mgIn Stock
$450.00
1
10mgIn Stock
$750.00
1
25mgIn Stock
$1,250.00
1
50mgIn Stock
$2,050.00
1
100mgIn Stock
$3,450.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $150.00 | In Stock | 1 | |
| 5mg | $450.00 | In Stock | 1 | |
| 10mg | $750.00 | In Stock | 1 | |
| 25mg | $1,250.00 | In Stock | 1 | |
| 50mg | $2,050.00 | In Stock | 1 | |
| 100mg | $3,450.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Chemical Properties
CAS No.
275375-69-4
Synonyms
BMS-223131; BMS 223131; BMS223131
SMILES
C1=CC2=C(C=C1C(F)(F)F)C(=C(C(=O)N2)CCO)C3=C(C=CC(=C3)Cl)O
Molecular Formula
C18H13ClF3NO3
Molecular Weight
383.7512
Solubility
To be determined
Storage
Store at-20℃
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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