GLPBio

BPH-715

Catalog No.: GC65355Purity:>98.00%
BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells.

Products are for research use only. Not for human use. We do not sell to patients.


BPH-715
Cas No.: 1059677-23-4
1mgIn Stock
$154.00
1
5mgIn Stock
$362.00
1
10mgIn Stock
$481.00
1

Citations

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    Nature
    641, 529–536 (2025)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells[1].

[1]. Singh AP, et al. Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth. Antimicrob Agents Chemother. 2010 Jul;54(7):2987-93.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
1059677-23-4
Molecular Formula
C17H31NO7P2
Molecular Weight
423.38
Solubility
0.5 M NaOH : 80 mg/mL (188.96 mM; ultrasonic and adjust pH to 11 with NaOH)|DMSO : 5 mg/mL (11.81 mM; ultrasonic and warming and heat to 60°C)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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