GLPBio

C10-200

Catalog No.: GC91832Purity:>95.00%
COASDSData Sheet
C10-200 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.

Products are for research use only. Not for human use. We do not sell to patients.

C10-200
Cas No.: N/A
5 mgIn Stock
$97.00
1
10 mgIn Stock
$174.00
1
25 mgIn Stock
$339.00
1
50 mgIn Stock
$580.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

C10-200 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.[1] LNPs containing C10-200 and encapsulating mRNA encoding a luciferase reporter selectively induce luminescence in the livers of mice to a greater extent than LNPs containing the branched-chain ionizable cationic lipidoid C12-200 . LNPs containing C10-200 and encapsulating mRNA encoding erythropoietin (EPO) increase serum levels of EPO in mice.

References:
[1].Mrksich, K., Padilla, M.S., Joseph, R.A., et al.Influence of ionizable lipid tail length on lipid nanoparticle delivery of mRNA of varying lengthJ. Biomed. Mater. Res. A(2024).

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
N/A
Molecular Formula
C60H125N5O5
Molecular Weight
996.7
Solubility
Chloroform: Sparingly soluble: 1-10 mg/ml,Ethanol: Soluble: ≥10 mg/mL
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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