GLPBio

C201-0243

Catalog No.: GC81485Purity:>99.50%
COASDSData Sheet
C201-0243 is a FcRn antagonist.

Products are for research use only. Not for human use. We do not sell to patients.

C201-0243
Cas No.: 931360-60-0
10mgIn Stock
$151.00
1
25mgIn Stock
$302.00
1
50mgIn Stock
$486.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

C201-0243 is a FcRn antagonist. C201-0243 exhibits antagonistic activity against IgG-FcRn binding with an IC50 of 3.439 nM. C201-0243 can be used in the research of IgG-mediated autoimmune diseases [1].

References:
[1]. Wu G, et al. Virtual Screening Combined with Phase Transition-FRET for Discovery of Small-Molecule FcRn Antagonists. Anal Chem. 2025 May 27;97(20):10661-10670.

Product Documents

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
931360-60-0
Molecular Formula
C18H16FN3O3
Molecular Weight
341.34
Solubility
DMSO: 4 mg/mL (11.72 mM; Need warming)
Storage
Store at 4°C, stored under nitrogen
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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