C22 Ceramide (86950-30-14) is a long-chain ceramide containing behenic acid. Mitochondrial-to-cytosolic stress response (MCSR) is a recently identified stress response which can be induced by increased synthesis of fatty acids. C22-ceramide is an endogenous signaling lipid which specifically inhibits MCSR with no effect on unfolded protein responses within the mitochondria. Hearts overexpressing Acyl CoA synthetase1 contain elevated levels of C22-ceramide.
C22 Ceramide
Catalog No.: GB40135Purity:>98%
C22 Ceramide (86950-30-14) is a long-chain ceramide containing behenic acid. Mitochondrial-to-cytosolic stress response (MCSR) is a recently identified stress response which can be induced by increased synthesis of fatty acids. C22-ceramide is an endogenous signaling lipid which specifically inhibits MCSR with no effect on unfolded protein responses within the mitochondria. Hearts overexpressing Acyl CoA synthetase1 contain elevated levels of C22-ceramide.
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Cas No.: 86950-30-4
2mgIn Stock
$165.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 2mg | $165.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Chemical Properties
CAS No.
86950-30-4
Molecular Formula
C40H79NO3
Molecular Weight
622.06
Solubility
Ethanol : 5 mg/mL (8.04 mM; ultrasonic and warming and heat to 60°C); DMF : 0.33 mg/mL (0.53 mM; ultrasonic and warming and heat to 60°C)
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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