CD12681 is a potent RORγ inverse agonist with an IC50 value of 19 nM. CD12681 showed in vivo activity in an IL-23 induced skin inflammation model in mouse. Preclinical candidate for the topical treatment of psoriasis.
CD12681
Catalog No.: GB40141Purity:>98%
CD12681 is a potent RORγ inverse agonist with an IC50 value of 19 nM. CD12681 showed in vivo activity in an IL-23 induced skin inflammation model in mouse. Preclinical candidate for the topical treatment of psoriasis.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1952239-59-6
10mgIn Stock
$446.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mg | $446.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Chemical Properties
CAS No.
1952239-59-6
Molecular Formula
C25H33N3O4S
Molecular Weight
471.61
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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