GLPBio

Choline tosylate

Catalog No.: GC76946Purity:>99.00%Synonyms: Choline p-toluenesulfonate
Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C.

Products are for research use only. Not for human use. We do not sell to patients.


Choline tosylate
Cas No.: 55357-38-5
10mM (in 1mL DMSO)In Stock
$12.00
1
5 gIn Stock
$11.00
1
10 gIn Stock
$18.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG)[1][2].

References:
[1]. Yu L, et al. The interaction of phospholipase A2 with phospholipid analogues and inhibitors. J Biol Chem. 1990 Feb 15;265(5):2657-64.
[2]. Trousil S. Choline Kinase Inhibition as a Treatment Strategy of Cancers with Deregulated Lipid Metabolism. Imperial College London, 2014.

Product Documents

Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
55357-38-5
Synonyms
Choline p-toluenesulfonate
Molecular Formula
C12H21NO4S
Molecular Weight
275.36
Solubility
DMSO: 100 mg/mL (363.16 mM; Need ultrasonic)
Storage
4°C, sealed storage, away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

Review for Choline tosylate

Rating: 5
  • 5 Star100%
  • 4 Star0%
  • 3 Star0%
  • 2 Star0%
  • 1 Star0%