GLPBio

CP-312

Catalog No.: GC70571Purity:>99.00%
COASDSData Sheet
CP-312 is a potent Heme Oxygenase-1 (HO-1) inducer.

Products are for research use only. Not for human use. We do not sell to patients.

CP-312
Cas No.: 895470-67-4
1 mgIn Stock
$41.00
1
5 mgIn Stock
$86.00
1
10 mgIn Stock
$131.00
1
25 mgIn Stock
$225.00
1
50 mgIn Stock
$329.00
1
100 mgIn Stock
$468.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

CP-312 is a potent Heme Oxygenase-1 (HO-1) inducer. CP-312 protects hiPSC-CM viability by targeting the antioxidant response network through induction of HMOX1 expression. CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress.

CP-312 (10 µM; 2 h) exhibits good potency in protecting hiPSC-CMs from acute peroxide-induced cell death with EC50 = 6.7 µM[1].

References:
[1]. Kirby RJ, et, al. Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress. J Pharmacol Exp Ther. 2018 Jan;364(1):87-96.

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
895470-67-4
Molecular Formula
C16H12ClN3OS2
Molecular Weight
361.87
Solubility
DMSO : 125 mg/mL (345.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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