GLPBio

Cys-MC-GGFG-Dxd-d5 TFA

Catalog No.: GC79838Purity:>98.00%Synonyms: Cys-MC-GGFG-Dxd-d 5 TFA
COASDSData Sheet
Cys-MC-GGFG-Dxd -d5 TFA (Cys-MC-GGFG-Dxd-d 5 TFA) is the deuterium labeled Cys-MC-GGFG-Dxd.

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Cys-MC-GGFG-Dxd-d5 TFA
1mgIn Stock
$324.00
1
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

Cys-MC-GGFG-Dxd -d5 TFA (Cys-MC-GGFG-Dxd-d 5 TFA) is the deuterium labeled Cys-MC-GGFG-Dxd. Cys-MC-GGFG-Dxd -d5 TFA is a conjugate of Cys and Deruxtecan. Cys-MC-GGFG-Dxd -d5 TFA is a linker-toxin building block in antibody-drug conjugates (ADCs) used to link antibody Cys residues to cytotoxic drugs. Cys-MC-GGFG-Dxd -d5 TFA can be used in cancer research [1] [2].

References:
[1]. Peng H. Perspectives on the development of antibody-drug conjugates targeting ROR1 for hematological and solid cancers. Antib Ther. 2021 Oct 15;4(4):222-227.
[2]. Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

Synonyms
Cys-MC-GGFG-Dxd-d 5 TFA
Molecular Formula
C57H59D5F4N10O17S
Molecular Weight
1274.26
Solubility
DMSO: 100 mg/mL (78.48 mM; Need ultrasonic)
Storage
Store at -20°C, away from moisture
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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