GLPBio

Dacomitinib hydrate

Catalog No.: GC72889Purity:>98.00%Synonyms: PF-00299804 hydrate; PF-299804 hydrate
COASDSData Sheet
Dacomitinib (PF-00299804) drate is an orally active, irreversible pan-ErbB inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.

Dacomitinib hydrate
Cas No.: 1042385-75-0
1mgIn Stock
$21.00
1
5mgIn Stock
$50.00
1
10mgIn Stock
$76.00
1
25mgIn Stock
$133.00
1
50mgIn Stock
$214.00
1
100mgIn Stock
$305.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Dacomitinib (PF-00299804) drate is an orally active, irreversible pan-ErbB inhibitor. Dacomitinib drate can be used in the research of cancers such as metastatic non-small cell lung cancer (NSCLC).

References:
[1]. Lau SCM, et al. Dacomitinib in the Management of Advanced Non-Small-Cell Lung Cancer. Drugs. 2019 Jun;79(8):823-831.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1042385-75-0
Synonyms
PF-00299804 hydrate; PF-299804 hydrate
Molecular Formula
C24H27ClFN5O3
Molecular Weight
487.95
Solubility
DMSO : ≥ 48.33 mg/mL (99.05 mM)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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