Dapsone-d8 |
| Catalog No.GC47172 |
An internal standard for the quantification of daspone
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 557794-38-4
Sample solution is provided at 25 µL, 10mM.
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Dapsone-d8 is intended for use as an internal standard for the quantification of dapsone by GC- or LC-MS. Dapsone is an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders.1 Dapsone is acetylated in the liver to monoacetyldapsone, the major metabolite, and other mono and diacetyl derivatives, and subsequently deacetylated back to diaminodiphenylsulfone (dapsone) until a state of equilibrium is achieved.
1.Bonde, S.L., Bhadane, R.P., Gaikwad, A., et al.Simultaneous determination of Dapsone and its major metabolite N-acetyl Dapsone by LC-MS/MS methodInt. J. Pharm. Pharm. Sci.5(Suppl 3)441-446(2013)
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