Control Liposomes(PBS)

Disodium clodronate is a specific macrophage-killing agent that can eliminate macrophages in tissues by inducing macrophage apoptosis. The ideal reagent currently available on the market for highly efficient macrophage depletion is liposomal disodium clodronate, where disodium clodronate molecules are encapsulated in lipid vesicles, offering high activity, stability, and ease of use. After intravenous injection of 0.2 mL liposomal disodium clodronate, macrophage clearance rates in the spleen (red pulp macrophages) reach 80%-90% within 24 hours.