GLPBio

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products Related to Drug Metabolite(546)

  • GC10822 structure
    GC10822Clozapine N-oxide (CNO)
    CAS: 34233-69-7
    Purity: >98.00%

    Clozapine N-oxide (CNO) ist ein potenter Dopamin-Antagonist und gleichzeitig ein potenter und selektiver Agonist des muskarinischen M4-Rezeptors(EC 50 =11 nM).

  • GC11155 structure
    GC11155Omeprazole sulfone
    CAS: 88546-55-8
    Purity: >98%

    Omeprazolsulfon ist ein Metabolit von Omeprazol, einem Protonenpumpenhemmer.

  • GC11989 structure
    GC11989Nortriptyline (hydrochloride)
    CAS: 894-71-3
    Purity: >99.50%

    Nortriptylin (Hydrochlorid) (Desmethylamitriptylin-Hydrochlorid), der aktive Hauptmetabolit von Amitriptylin, ist ein trizyklisches Antidepressivum, das zur Linderung der Symptome einer Depression angewendet wird.

  • GC12685 structure
    GC12685Ercalcitriol
    CAS: 60133-18-8
    Purity: >99.00%

    A potent agonist of the vitamin D receptor

  • GC14762 structure
    GC14762Palifosfamide
    CAS: 31645-39-3
    Purity: >98%

    An active metabolite of ifosfamide

  • GC14780 structure
    GC14780Oseltamivir acid
    CAS: 187227-45-8
    Purity: >98.00%

    A neuraminidase inhibitor and antiviral

  • GC15168 structure
    GC15168Urolithin A
    CAS: 1143-70-0
    Purity: >98.50%

    Ein Darmmikroben-Metabolit von Ellagsäure.

  • GC16292 structure
    GC16292Equol
    CAS: 94105-90-5
    Purity: >98.00%

    Equol ist das Racemat von Equol.

  • GC16333 structure
    GC16333Cycloguanil (hydrochloride)
    CAS: 152-53-4
    Purity: >99.50%

    Cycloguanil (Hydrochlorid), der aktive Metabolit von Proguanil, wirkt auf Malaria-Schizonten in Erythrozyten und Hepatozyten.

  • GC16553 structure
    GC16553N-Desmethylclozapine
    CAS: 6104-71-8
    Purity: >99.50%

    N-Desmethylclozapin ist ein wichtiger aktiver Metabolit des atypischen Antipsychotikums Clozapin.

  • GC18194 structure
    GC181944-Epidoxycycline
    CAS: 6543-77-7
    Purity: >98%

    4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline .

  • GC18219 structure
    GC182196-hydroxy Warfarin
    CAS: 17834-02-5
    Purity: >98.00%

    6-hydroxy Warfarin is a metabolite of (+)-warfarin , which is a weaker vitamin K antagonist than (-)-warfarin .

  • GC18335 structure
    GC183356β-hydroxy Dexamethasone
    CAS: 55879-47-5
    Purity: >98%

    6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound.

  • GC18417 structure
    GC184174-hydroxy Xylazine
    CAS: 145356-32-7
    Purity: >97.50%

    4-Hydroxy-Xylazin ist ein Metabolit von Xylazin.

  • GC18425 structure
    GC184254-hydroxy Atorvastatin lactone
    CAS: 163217-70-7
    Purity: >98%

    4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.

  • GC18439 structure
    GC18439Doxorubicinone
    CAS: 24385-10-2
    Purity: >95.00%

    Doxorubicinon ist ein Metabolit eines Chemotherapeutikums gegen Krebs, Doxorubicin. Doxorubicin ist ein potenter Human-DNA-Topoisomerase-I- und -Topoisomerase-II-Inhibitor mit IC50-Werten von 0,8μM bzw. 2,67μM.

  • GC18455 structure
    GC18455Digoxigenin Monodigitoxoside
    CAS: 5352-63-6
    Purity: >98%

    Digoxigenin-Monodigitoxosid ist ein Na+/K+-ATPase-Hemmer und Herzglykosid-Metabolit von Digoxin.

  • GC18466 structure
    GC184665,6-epoxy-13-cis Retinoic Acid
    CAS: 81444-57-7
    Purity: >98%

    5,6-epoxy-13-cis Retinoic acid is a metabolite of 13-cis retinoic acid.

  • GC18527 structure
    GC185274'-hydroxy Flurbiprofen
    CAS: 52807-12-2
    Purity: >98%

    A major active metabolite of flurbiprofen

  • GC18539 structure
    GC185394-Hydroxyretinoic acid (4-HRA)
    CAS: 66592-72-1
    Purity: >98.00%

    4-Hydroxyretinoic acid (4-HRA) is a naturally occurring, primary metabolite derived from all-trans retinoic acid (ATRA) via cytochrome P450 enzyme metabolism.

  • GC18542 structure
    GC185425,6-dihydro-5-Fluorouracil
    CAS: 696-06-0
    Purity: >95.00%

    5,6-dihydro-5-Fluorouracil (5-FUH2) is formed by the hydrogenation of 5-fluorouracil via the enzyme dihydropyrimidine dehydrogenase (DPD).

  • GC18569 structure
    GC18569Propofol β-D-Glucuronide
    CAS: 114991-26-3
    Purity: >98.00%

    Propofol β-D-Glucuronide is a metabolite of propofol and is widely used as a marker to identify the metabolic status of propofol in animals.

  • GC18582 structure
    GC185825'-hydroxy Meloxicam
    CAS: 130262-92-9
    Purity: >98%

    A metabolite of meloxicam

  • GC18596 structure
    GC18596(±)-2-propyl-4-Pentenoic Acid
    CAS: 1575-72-0
    Purity: >98.00%

    (±)-2-Propyl-4-pentensÄure (4-en-VPA) ist ein wichtiger toxischer Metabolit von ValproinsÄure.