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GLP-1 receptor agonist 14

Katalog-Nr.GC73720

GLP-1 receptor agonist 14 (Verbindung 73) ist ein starker Agonist von Glukagon-ähnlichem Peptid-1 (GLP-1).

Products are for research use only. Not for human use. We do not sell to patients.

GLP-1 receptor agonist 14 Chemische Struktur

Cas No.: 3011682-51-9

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Sample solution is provided at 25 µL, 10mM.

Description of GLP-1 receptor agonist 14

GLP-1 receptor agonist 14 (compound 73) is a potent agonist of glucagon-like peptide-1 (GLP-1). GLP-1 receptor agonist 14 plays an important role in diabetes or other metabolic disorders.

References:
[1]. Ren Zaifang, et al. Preparation of tetradropyrazolo-pyrazinyl-didroimidazolone or tetradropyrazolo-pyridinyl-didroimidazolone compounds as GLP-1 receptor modulators and methods of using same. World Intellectual Property Organization, WO2022017338 A1 2022-01-27

Chemical Properties of GLP-1 receptor agonist 14

Cas No. 3011682-51-9 SDF
Formula C48H46F2N10O5 M.Wt 880.94
Löslichkeit Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of GLP-1 receptor agonist 14

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.1352 mL 5.6758 mL 11.3515 mL
5 mM 0.227 mL 1.1352 mL 2.2703 mL
10 mM 0.1135 mL 0.5676 mL 1.1352 mL
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In vivo Formulation Calculator (Clear solution) of GLP-1 receptor agonist 14

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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