Leukotrienes

Sulochrin ist ein von A. produziertes Pilzmetabolit.

5-Lipoxygenase (5-LO) catalyzes the biosynthesis of leukotrienes, which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction.

Microsomal Prostaglandin E2 Synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever and pain.

Leukotriene A4 (LTA4) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities.

Leukotrien F4 (LTF4) ist ein Lipid, das zur Familie der Cysteinyl-Leukotriene (CysTL) gehÖrt.

5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs) from arachidonic acid, primarily in certain leukocyte populations.

Leukotrien B4 (LTB4) ist als einer der stÄrksten chemischen Lockstoffe und Aktivatoren von Leukozyten bekannt und an entzÜndlichen Erkrankungen beteiligt.

LTB3 is the LTA hydrolase metabolite of LTA3 in the leukotriene biosynthetic pathway.

(±)14(15)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450.

The effects of leukotriene B4 (LTB4) are mediated by two receptors, BLT1 and BLT2.

Biosynthesis of LTA3 occurs from 5,8,11-eicosatrienoic acid via the 5-LO pathway and it is the putative intermediate in the biosynthesis of 3-series leukotrienes.

Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway.

Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway.

Leukotriene B5 (LTB5) is a leukotriene with diverse biological activities.

Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes.

6-trans-Leukotrien B4 ist ein neutrophiles Chemotaxin in der Dermis von Meerschweinchen.

6-trans-12-epi Leukotrien B4, ein Arachidonsäure-Metabolit, ist ein starkes entzündungshemmendes Mittel.

11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4.

Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes.

11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4.

14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates.

11-trans-Leukotrien E4 ist ein Isomer von Leukotrien E4 (LTE4).

Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes.

14,15-Leukotriene A4 (14,15-LTA4) methyl ester is an esterified form of 14,15-LTA4, a leukotriene isomer formed from arachidonic acid by 15-lipoxygenase (15-LO) that inhibits LTA4 hydrolase.