Hydroxy/Hydroperoxy/Epoxy/Oxo Eicosanoids

12(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 12-lipoxygenase on eicosapentaenoic acid.

15(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosapentaenoic acid.

5(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-LO on EPA.

(±)12-HpETE is one of the six monohydroperoxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid and consists of an equal mixture of the R and S isomers.

Eicosapentaenoic acid is an ω-3 fatty acid abundantly available in marine organisms.

Eicosapentaenoic acid is an ω-3 fatty acid abundantly available in marine organisms.

Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.

(±)8,9-DiHETE is a major metabolite of the 20:5 ω-3 fatty acid eicosapentaenoic acid.

15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid.

5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid.

5(S),15(S)-DiHETE ist ein „aktiviertes“ Intermediat, hemmt die Thrombozytenaggregation mit einem IC50 von 1,3 μM.

5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor.

5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4).

8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO.

(±)11,12-DiHETE is a dihydroxy metabolite of EPA produced by cytochrome P450-mediated epoxide formation and subsequent hydrolysis by epoxide hydrolase.

FOG9 is formed through the conjugation of 5-oxoETE with glutathione in a 1,6 Michael addition at C-9.

(±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide.

(±)17(18)-EpETE methyl ester is an analog of the eicosapentaenoic acid (EPA) metabolite (±)17(18)-EpETE that is more lipid soluble.

(±)5(6)-EpETE methyl ester is a derivative of 5(6)-EpETE which is stable enough to ship and handle routinely.

5-OxoETE methyl ester is an esterified form of the polyunsaturated keto acid 5-oxoETE.

2-hydroxy Arachidic acid is a hydroxylated fatty acid that has been found in pasture grass (S.

15(S)-HpEDE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosadienoic acid.

Arachidonyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic activity, binding to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.

Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes.