Sphingolipids

C6 NBD phytoceramide is a biologically active derivative of C6 phytoceramide that is tagged with a fluorescent C6 nitrobenzoxadiazole group.

D-threo Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and L-erythro sphinganine (d18:0).

L-erythro Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and D-threo sphinganine.

FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.

Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase.

Sphingosines are long-chain base precursors of cellular sphingolipids used directly in the synthesis of ceramide, which in combination with sialic acid forms ganglioside.

The lipid messenger ceramide is converted to glucosylceramide by glucosylceramide synthase (GCS).

CAY10739 ist ein selektiver S1PR1-Inhibitor mit einem pIC50 von 7,6 und einer >40- und >80-fachen SelektivitÄt gegenÜber den anderen S1PR-Isoformen S1PR2/3/4.

1-Deoxysphingosine (m18:1(14Z)) is an atypical sphingolipid that contains a double bond at the n-4 (14Z) native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.

(E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal that can be used as a click chemistry probe.

13C C16 Sphingomyelin is an isotopically enriched form of C16 sphingomyelin with carbon-13 occurring on the fatty acid portion.

13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS.

1-β-D-Glucosylsphingadienin (d18:2 (4E,8E)) ist ein Glucosylsphingosin, das deacetylierte Lysolipidderivate von Glucosylcerebrosiden sind.

1-β-D-Glucosylsphingosine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucocerebrosides.

Sphingosine-1-phosphate (S1P) lyase catalyzes the irreversible decomposition of S1P to hexadecanaldehyde and phosphoethanolamine.

3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group.

3-keto Sphinganine (d12:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0).

3-keto Sphinganine is an intermediate in the biosynthesis of C18 ceramide (d18:1/18:0).

3-keto Sphinganine (d6:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0).

3-keto Sphinganine (d8:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0).

4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities.

ARN14988 ist ein starker Inhibitor der sauren Ceramidase (ACDase) (IC50 = 12,8 nM fÜr das menschliche Enzym).

Azido-FTY720 ist ein photoaktivierbares Analogon von FTY720.

BODIPY-C12 Ceramide (d18:1/12:0) is a fluorescently labeled C12 ceramide.