(±)-ANAP is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.
(±)-ANAP is the amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity with comparable or increased brightness[1]. (±)-ANAP is sensitive to polarity with changes in intensity and emission wavelength[2].
[1]. Lee HS, et al. Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiae. J Am Chem Soc. 2009 Sep 16;131(36):12921-3. [2]. Xiang Z, et al. Enantiospecific synthesis of genetically encodable fluorescent unnatural amino acid L-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid. J Org Chem. 2011 Aug 5;76(15):6367-71.