DSG-PEG2000-OH is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal hydroxyl groups (-OH). DSG-PEG2000-OH combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
In Vitro, The structure of DMG-PEG-OH comprises three key components that work synergistically: DMG: Acts as a hydrophobic anchor, securely embedding the entire molecule into the membrane structure of lipid nanoparticles. PEG chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, and prolonging the carrier's circulation time in vivo. Hydroxyl group (-OH): It is an active group that can serve as a starting point for further chemical reactions, such as coupling drug molecules, linking other targeted ligands, or modifying material surfaces.
In Vitro, The structure of DMG-PEG-OH comprises three key components that work synergistically: DMG: Acts as a hydrophobic anchor, securely embedding the entire molecule into the membrane structure of lipid nanoparticles. PEG chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, and prolonging the carrier's circulation time in vivo. Hydroxyl group (-OH): It is an active group that can serve as a starting point for further chemical reactions, such as coupling drug molecules, linking other targeted ligands, or modifying material surfaces.