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DSPE-NHS

Catalog No.GC72674 Copy One-Click Copy Product Info

DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails.

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DSPE-NHS Chemical Structure

Cas No.: 1383932-86-2

Size Price Stock Qty
5 mg
$45.00
In stock
10 mg
$72.00
In stock
25 mg
$144.00
In stock
50 mg
$234.00
In stock
100 mg
$351.00
In stock

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Customer Reviews

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Sample solution is provided at 25 µL, 10mM.



Description of DSPE-NHS

DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. DSPE-NHS can be used to prepare liposomes as agent nanocarrier.

References:
[1]. Mikio Tatsutomi, et al. Preparation of a nitric oxide imaging agent from gelatin derivative micelles. Regen Ther. 2016 Sep 14;5:64-71.

Chemical Properties of DSPE-NHS

Cas No. 1383932-86-2 SDF
Formula C49H89N2O13P M.Wt 945.21
Solubility Storage -20°C, sealed storage, away from moisture and light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of DSPE-NHS

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.058 mL 5.2898 mL 10.5797 mL
5 mM 211.6 μL 1.058 mL 2.1159 mL
10 mM 105.8 μL 529 μL 1.058 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of DSPE-NHS

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Reviews

Review for DSPE-NHS

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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