GLPBio

DSPE-PEG2000-tetrazine

Catalog No.: GC79692Purity:>98%
COASDSData Sheet
DSPE-PEG2000-tetrazine is a synthetic phospholipid modified with PEG2000 and tetrazine moieties.

Products are for research use only. Not for human use. We do not sell to patients.

DSPE-PEG2000-tetrazine
Cas No.: 3101670-39-4
1mgIn Stock
$194.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

DSPE-PEG2000-tetrazine is a synthetic phospholipid modified with PEG2000 and tetrazine moieties. DSPE-PEG2000-tetrazine gains improved steric stability via PEGylation. DSPE-PEG2000-tetrazine enables bioorthogonal click chemistry through its tetrazine segment, which selectively reacts with trans-cyclooctene ( TCO ) under complex biological environments. DSPE-PEG2000-tetrazine can be applied for researches related to click chemistry [1].

In Vitro, DSPE-PEG2000-tetrazine enables successful conjugation of Rhodamine-CRM197-TCO to PLGA/lipid hybrid nanoparticles via TCO-tetrazine click chemistry[1].

References:
[1]. Hu H, et al. Conjugation of Multiple Proteins Onto the Surface of PLGA/Lipid Hybrid Nanoparticles. J Biomed Mater Res A. 2025;113(1):e37807.

Chemical Properties

CAS No.
3101670-39-4
Molecular Weight
2000
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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