GLPBio

F2201

Catalog No.: GC43647Purity:>98.00%Synonyms: 5-fluoro JWH 412, ​JWH 412 5-fluoropentyl analog

AM2201 is a potent synthetic cannabinoid (CB) that binds the CB1 and CB2 receptors with high affinity (Kis = 1.0 and 2.6 nM, respectively).

Products are for research use only. Not for human use. We do not sell to patients.


F2201
Cas No.: 1391485-39-4
1mgIn Stock
$113.00
1
5mgIn Stock
$498.00
1
10mgIn Stock
$830.00
1
25mgIn Stock
$1,658.00
1

Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    31, 1291–1307 (2021)

Description

AM2201 is a potent synthetic cannabinoid (CB) that binds the CB1 and CB2 receptors with high affinity (Kis = 1.0 and 2.6 nM, respectively). [1]  F2201 is an analog of AM2201 with a fluorine at the 4 position of the naphthyl group. The physiological and toxicological properties of this compound have not been delineated. This product is intended for research and forensic purposes.

Reference:
1. Makriyannis, A., and Deng, H. Cannabimimetic indole derivatives. PCT/US00/28832, (2001).

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
1391485-39-4
Synonyms
5-fluoro JWH 412, ​JWH 412 5-fluoropentyl analog
Chemical Name
(4-fluoro-1-naphthalenyl)[1-(5-fluoropentyl)-1H-indol-3-yl]-methanone
SMILES
O=C(C1=CC=C(F)C2=C1C=CC=C2)C3=CN(C4=C3C=CC=C4)CCCCCF
Molecular Formula
C24H21F2NO
Molecular Weight
377.4
Solubility
5mg/mL in ethanol, 20mg/mL in DMSO, or in dichloromethane, or in DMF
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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