2-(2-Chlorobenzamido)acetic acid is an aldose reductase inhibitor with an IC50 of 31 μM. 2-(2-Chlorobenzamido)acetic acid can be used for the research of chronic diabetes [1].
In Vitro, 2-(2-Chlorobenzamido)acetic acid (Compound 6h) inhibits cell-free partially purified aldose reductase (from rat lens) with an IC50 of 31 μM[1].
References:
[1]. DeRuiter J, et al. Synthesis and in vitro aldose reductase inhibitory activity of compounds containing an N-acylglycine moiety. J Med Chem. 1989;32(5):1033-1038.
In Vitro, 2-(2-Chlorobenzamido)acetic acid (Compound 6h) inhibits cell-free partially purified aldose reductase (from rat lens) with an IC50 of 31 μM[1].
References:
[1]. DeRuiter J, et al. Synthesis and in vitro aldose reductase inhibitory activity of compounds containing an N-acylglycine moiety. J Med Chem. 1989;32(5):1033-1038.