3-(3-Sulfooxyphenyl) propanoic acid disodium is a metabolite of Echinacoside. 3-(3-Sulfooxyphenyl) propanoic acid disodium promotes neural, psychological and brain health, enhances the proliferation, function and activity of brain cells, and facilitates extinction learning. 3-(3-Sulfooxyphenyl) propanoic acid disodiumis can be used in research related to anxiety disorders, post-traumatic stress disorder, extinction learning deficits, autism, as well as neurodegenerative diseases including Parkinson's disease and Alzheimer's disease [1] [2].
In Vivo, 3-(3-Sulfooxyphenyl) propanoic acid disodium (compound M14) is the hydrogenated metabolite produced after oral administration of Echinacoside to male SD rats[2].
References:
[1]. David ARTIS, et al. Microbiota based therapies to promote mental health. WO2021081247A1.
[2]. Song Q, et al. Retention Time and Optimal Collision Energy Advance Structural Annotation Relied on LC-MS/MS: An Application in Metabolite Identification of an Antidementia Agent Namely Echinacoside. Anal Chem. 2019 Dec 3;91(23):15040-15048.
In Vivo, 3-(3-Sulfooxyphenyl) propanoic acid disodium (compound M14) is the hydrogenated metabolite produced after oral administration of Echinacoside to male SD rats[2].
References:
[1]. David ARTIS, et al. Microbiota based therapies to promote mental health. WO2021081247A1.
[2]. Song Q, et al. Retention Time and Optimal Collision Energy Advance Structural Annotation Relied on LC-MS/MS: An Application in Metabolite Identification of an Antidementia Agent Namely Echinacoside. Anal Chem. 2019 Dec 3;91(23):15040-15048.