(3β,4β,17β)-17-(2-Pyridinylmethyl)androst-5-ene-3,4,17-triol is a sterol lipid and derivative of 5-androstenetriol .[1] It is cytotoxic to MDA-MB-231 breast, PC3 prostate, HeLa cervical, and HT-29 colon cancer cells (IC50s = 9, 52.1, 26.6, and 8 µM, respectively) but not MRC-5 fibroblasts (IC50 = >100 µM).
References:
[1].Djurendić, E.A., Ajduković, J.J., Sakač, M.N., et al.Synthesis and cytotoxic activity of some 17-picolyl and 17-picolinylidene androstane derivativesEur. J. Med. Chem.54784-792(2012).