Arg-Gly-Asp (trifluoroacetate salt) (Synonyms: RGD) |
Catalog No.GC52474 |
A synthetic peptide corresponding to an integrin cell adhesion sequence
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 120103-89-1
Sample solution is provided at 25 µL, 10mM.
Arg-Gly-Asp (RGD) is a synthetic peptide corresponding to the cell adhesion sequence for the integrins αVβ1, αVβ3, αVβ5, αVβ6, αVβ8, α8β1, and α5β1.1,2 It is a component of radioligands and peptidomimetics that have been used in the study of integrin expression and activity in vivo.2,3
1.Ruoslahti, E.RGD and other recognition sequences for integrinsAnnu. Rev. Cell Dev. Biol.12697-715(1996) 2.Danhier, F., Le Breton, A., and PrÉat, V.RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosisMol. Pharm.9(11)2961-2973(2012) 3.Schottelius, M., Laufer, B., Kessler, H., et al.Ligands for mapping αvβ3-integrin expression in vivoAcc. Chem. Res.42(7)969-980(2009)
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