BAS00093476 is an E-cadherin inhibitor. BAS00093476 exhibits inhibitory activity against E-cadherin -mediated cell-cell adhesion in human pancreatic tumor BxPC-3 cells. BAS00093476 can be applied to the research on the modulation of E-cadherin -mediated cell-cell adhesion in solid tumors expressing cadherins [1].
References:
[1]. Dalle Vedove A, et al. Structure-Based Virtual Screening Allows the Identification of Efficient Modulators of E-Cadherin-Mediated Cell-Cell Adhesion. Int J Mol Sci. 2019 Jul 11;20(14):3404.
References:
[1]. Dalle Vedove A, et al. Structure-Based Virtual Screening Allows the Identification of Efficient Modulators of E-Cadherin-Mediated Cell-Cell Adhesion. Int J Mol Sci. 2019 Jul 11;20(14):3404.