Catestatin sCst TFA is a scrambled control peptide that serves as a negative control for Catestatin TFA [1] [2].
In Vitro, Catestatin sCst (20 μM; 1-6 h) TFA does not stimulate IL-8 mRNA expression in normal human keratinocytes[2]. Catestatin sCst (20 μM; 24 h) TFA does not stimulate IL-8 protein production from normal human keratinocytes[2]. Catestatin sCst (1.25 μM) TFA does not induce chemotaxis in normal human keratinocytes[2]. Catestatin sCst (10 μM; 5 min) TFA does not induce phosphorylation of ERK, p38, or JNK in normal human keratinocytes[2].
References:
[1]. Hoq MI, et al. Human catestatin enhances migration and proliferation of normal human epidermal keratinocytes. Journal of dermatological science. 2011 Nov;64(2):108-18.
[2]. Aung G, et al. A neuroendocrine antimicrobial peptide, catestatin, stimulates interleukin-8 production from human keratinocytes via activation of mitogen-activated protein kinases. J Dermatol Sci. 2011 Feb;61(2):142-4.
In Vitro, Catestatin sCst (20 μM; 1-6 h) TFA does not stimulate IL-8 mRNA expression in normal human keratinocytes[2]. Catestatin sCst (20 μM; 24 h) TFA does not stimulate IL-8 protein production from normal human keratinocytes[2]. Catestatin sCst (1.25 μM) TFA does not induce chemotaxis in normal human keratinocytes[2]. Catestatin sCst (10 μM; 5 min) TFA does not induce phosphorylation of ERK, p38, or JNK in normal human keratinocytes[2].
References:
[1]. Hoq MI, et al. Human catestatin enhances migration and proliferation of normal human epidermal keratinocytes. Journal of dermatological science. 2011 Nov;64(2):108-18.
[2]. Aung G, et al. A neuroendocrine antimicrobial peptide, catestatin, stimulates interleukin-8 production from human keratinocytes via activation of mitogen-activated protein kinases. J Dermatol Sci. 2011 Feb;61(2):142-4.