Chlorproethazine hydrochloride is an orally active phenothiazine compound. Chlorproethazine hydrochloride can eliminate spasticity when administered intravenously and also effectively reduce rigidity in decerebrate cats. Chlorproethazine hydrochloride can be used in the research of neurological diseases [1] [2] [3].
References:
[1]. Matthews WB. The action of chlorproethazine on spasticity. Brain. 1965 Dec;88(5):1057-64.
[2]. Barbaud A, et al. Contact sensitization to chlorproethazine can induce persistent light reaction and cross-photoreactions to other phenothiazines. Contact Dermatitis. 2001 Jun;44(6):373.
[3]. Keary EM, et al. A comparison of the effects of chlorpromazine and some related phenothiazines in reducing the rigidity of the decerebrate cat and in some other central actions. Br J Pharmacol Chemother. 1967 Jun;30(2):400-16.
References:
[1]. Matthews WB. The action of chlorproethazine on spasticity. Brain. 1965 Dec;88(5):1057-64.
[2]. Barbaud A, et al. Contact sensitization to chlorproethazine can induce persistent light reaction and cross-photoreactions to other phenothiazines. Contact Dermatitis. 2001 Jun;44(6):373.
[3]. Keary EM, et al. A comparison of the effects of chlorpromazine and some related phenothiazines in reducing the rigidity of the decerebrate cat and in some other central actions. Br J Pharmacol Chemother. 1967 Jun;30(2):400-16.