Coagulation & Hemostasis

A synthetic intermediate

TP specific agonist

6-hydroxy Warfarin is a metabolite of (+)-warfarin , which is a weaker vitamin K antagonist than (-)-warfarin .

Picotamide est un inhibiteur de l'agrégation plaquettaire avec une valeur d' IC 50 de 0.76μM.

11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.

Pimprinine is an alkaloid originally isolated from Streptomyces that has diverse biological activities, including anticonvulsant, antiplatelet, and antimicrobial properties.

Prostaglandin E1 (PGE1) is the theoretical cyclooxygenase metabolite of dihomo-γ-linolenic acid.

CTA2 is a stable analog of TXA2.

Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of DGLA, but to date it has not been isolated as a natural product.

5,7-Dihydroxy-4-methylcoumarin is a coumarin derivative from Mexican tarragon. 5,7-Dihydroxy-4-methylcoumarin possesses antifungal and antibacterial activities .

PAR4 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) and an amide form of PAR4 (1-6) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence.

PAR1 (1-6) is a hexapeptide that corresponds to amino acid residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat proteinase-activated receptor 1 (PAR1), residues 42-47 of the full-length mouse sequence, and residues 46-51 of the full-length rat sequence.

5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin.

7-hydroxy Warfarin is a metabolite of (-)-warfarin, which is a more potent vitamin K antagonist than (+)-warfarin.

Acenocoumarol is a short-lived oral anti-coagulant, which, like warfarin, functions by inhibiting vitamin K epoxide reductase.

Acenocoumarol is a short-lived oral anti-coagulant, which, like warfarin, functions by inhibiting vitamin K epoxide reductase.

6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions.

6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions.

Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid.

Prostaglandin D3 (PGD3) is produced by the metabolism of EPA via the COX pathway.

WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72 μM.

13,14-dehydro-15-cyclohexyl Carbaprostacyclin is a chemically stable analog of PGI2.

Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin.

Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin.