CRTH2
CRTh2 (chemoattractant receptor homologous molecule expressed on T-Helper type 2 cells ) is a G-protein coupled receptor for prostaglandin D2. Activation of CRTh2 increases the chemotaxis of Th2 cells/eosinophils/basophil, as well as eosinophil degranulation and Th2 cells cytokine release.
Products Related to CRTH2(2)
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC12434 | AZD1981 | 802904-66-1 | >99.50% | |
AZD1981 est un antagoniste puissant et sélectif de CRTh2; déplace la PGD2 radiomarquée de la DP2 recombinante humaine avec une puissance élevée (pIC50 = 8,4). | ||||
| GC13196 | NVP-QAV680 | 872365-16-7 | >98% | |
potent and selective CRTh2 receptor antagonist | ||||