Endocannabinoid/Endocannabinoid-like

L'éther de noladine est un agoniste puissant et sélectif du récepteur cannabinoÏde CB1, avec un Ki de 21,2 nM.

La N-Arachidonoyl Dopamine est un agoniste endogène puissant et sélectif des récepteurs CB1 avec un Ki de 250 nM.

An endocannabinoid

Prostaglandin E1 ethanolamide (PGE1-EA) is the ethanolamine-amide analog of PGE1.

A stable analog of PGF 2α 2glyceryl ester

Polyunsaturated fatty acids such as arachidonate and linoeate, while essential to health maintenance, are subject to random peroxidation by ambient oxygen, resulting in fragmented and reactive decomposition products.

Synaptamide (Dehydroepiandrosteron(DHEA)) est un ligand endogène du récepteur GPR110 (ADGRF1) qui stimule la production de cAMP, sa valeur d'EC50 est 1,27nM.

R-2 methanandamide is a cannabinoid analog with a methyl group in the (R) configuration at C-2 of the ethanolamine group.

2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.

2-O-Hexadecyl Glycerol is a β-monoglyceride of palmitic acid.

N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities.

The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.

Docosaenoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.

The endocannabinoids present a rich system of central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology that has stimulated research in many fields including memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation.

γ-Linolenoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called endocannabinoids.

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide.

The enzyme, fatty acid amide hydrolase (FAAH), is widely expressed in brain and other tissues, and is capable of hydrolyzing anandamide (AEA) and other simple esters and amides with long unsaturated acyl chains.

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide.

MAGL Inhibitor Compound 23 est un inhibiteur puissant, sélectif, réversible et compétitif de MAGL, avec une IC50 de 80 nM. Le composé inhibiteur MAGL 23 présente des effets anti-prolifératifs contre les cellules cancéreuses humaines du sein, colorectal et ovarien. Le composé inhibiteur de MAGL 23 bloque MAGL dans des tests cellulaires ainsi que des tests in vivo.

N-acylethanolamines (NAEs) are lipid-derived signaling compounds.

(±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide.

N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide binds to the cannabinoid 1 (CB1) receptor with a Ki value of 365 nM in a radioligand binding assay using rat brain homogenate.

Palmitoyl ethanolamide (PEA) is an endogenous cannabinoid found in brain, liver, and other mammalian tissues.

L'URB754 est un puissant inhibiteur de l'enzyme de désactivation des endocannabinoÏdes, la monoacylglycérol lipase (MGL) avec une IC50 de 200 nM.